Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364558 | 0.77 | SLC6A2 (0.50) | CHRM2CHRM1CHRM3 | |
| SCHEMBL10372236 | 0.74 | CYP19A1 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL11610907 | 0.73 | SLC6A3 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL461672 | 0.72 | IDO1 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30999488 | 0.72 | EPHX1 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30999484 | 0.72 | EPHX1 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4460887 | 0.72 | IDO1 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL244373 | 0.72 | CHRM2 (0.59) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL247653 | 0.72 | CHRM2 (0.59) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL245103 | 0.72 | CHRM2 (0.59) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790643-B1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE | ZHAO SHUQIANG (CN) | 2010-06-02 | — | — | EP | claimed |
| US-7521559-B2 | Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine | Zhao, Shuqiang (CN) | 2009-04-21 | — | — | US | claimed |
| US-20080247963-A1 | Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine | Zhao, Shuqiang (CN) | 2008-10-09 | — | — | US | claimed |
| EP-1790643-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE | Zhao, Shuqiang (CN) | 2007-05-30 | — | — | EP | claimed |
| US-8394824-B2 | Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine | SHUQIANG ZHAO (CN) | 2013-03-12 | — | — | US | disclosed |
| US-8207192-B2 | Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine | Zhao, Shuquiang (CN) | 2012-06-26 | — | — | US | disclosed |
| US-20120010236-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, ITS PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYLCHOLINE | Zhao, Shuqiang (CN) | 2012-01-12 | — | — | US | disclosed |
| EP-1790643-B1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE | ZHAO SHUQIANG (CN) | 2010-06-02 | — | — | EP | disclosed |
| US-20090163541-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, ITS PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYLCHOLINE | Zhao, Shuqiang (CN) | 2009-06-25 | — | — | US | disclosed |
| US-7521559-B2 | Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine | Zhao, Shuqiang (CN) | 2009-04-21 | — | — | US | disclosed |
| US-20080247963-A1 | Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine | Zhao, Shuqiang (CN) | 2008-10-09 | — | — | US | disclosed |
| EP-1790643-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE | Zhao, Shuqiang (CN) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080247963-A1 | Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine | CHRM1, CHRNA1, CHRM2 | CHRM2 3/4885CHRM4 14/4885CHRM5 8/4885 |
| US-20120010236-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, ITS PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYLCHOLINE | CHRM1, CHRNA1, CHRM2 | CHRM2 3/4885CHRM4 14/4885CHRM5 8/4885 |
| US-20090163541-A1 | QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, ITS PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYLCHOLINE | CHRM1, CHRNA1, CHRNG | CHRM2 5/4885CHRM4 17/4885CHRM5 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.