Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227131 | 0.83 | TSHR (0.47) | PABPC1TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL28874744 | 0.77 | TDP1 (0.44) | PABPC1TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL14625516 | 0.76 | KDM5A (0.41) | PABPC1TSHRALDH1A1HPGDKDM5A | |
| SCHEMBL28166832 | 0.75 | PABPC1 (0.52) | PABPC1TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL2292418 | 0.75 | ALDH1A1 (0.49) | PABPC1TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL448938 | 0.75 | MEN1 (0.50) | PABPC1TSHRDHODHALDH1A1HPGD | |
| SCHEMBL8763290 | 0.75 | ALDH1A1 (0.57) | PABPC1TSHRALDH1A1CYP2A6NPC1 | |
| SCHEMBL30527294 | 0.75 | ALDH1A1 (0.57) | PABPC1TSHRALDH1A1CYP2A6NPC1 | |
| SCHEMBL16319787 | 0.73 | PABPC1 (0.54) | PABPC1TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL20341641 | 0.73 | TDP1 (0.38) | PABPC1ALDH1A1CYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137103-A2 | INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2007-11-29 | — | — | WO | claimed |