Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | PPARG | P37231 | 17/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364847 | 1.00 | LMNA (0.66) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5364849 | 1.00 | LMNA (0.66) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5358338 | 1.00 | LMNA (0.66) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5358341 | 1.00 | LMNA (0.66) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5353508 | 0.85 | PPARA (0.56) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5369740 | 0.85 | PPARA (0.56) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5353512 | 0.85 | PPARA (0.56) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5353516 | 0.85 | PPARA (0.56) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL14501883 | 0.85 | PPARA (0.56) | LMNAL3MBTL1PPARAPPARGPPARD | |
| SCHEMBL5338861 | 0.84 | PPARA (0.75) | LMNAL3MBTL1PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | LMNA 2523/4885L3MBTL1 4691/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.