SCHEMBL536484

SCHEMBL536484

O=C[C@H](OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MPI P34949 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
BTN3A1 O00481 2/20 0.33
PDE4A P27815 1/20 0.32
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5165444 1.00 LMNA (0.37) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL3687102 1.00 LMNA (0.37) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL4082207 1.00 LMNA (0.37) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL8155983 0.98 LMNA (0.35) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL18486548 0.97 LMNA (0.34) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL18486485 0.97 LMNA (0.34) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL526988 0.95 MPI (0.37) LMNAL3MBTL1MPITDP1BTN3A1
Phosphoric Acid SCHEMBL19583205 0.93 MPI (0.36) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL321588 0.92 MPI (0.35) LMNAL3MBTL1MPITDP1BTN3A1
SCHEMBL30679810 0.91 MPI (0.33) LMNAL3MBTL1MPITDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11879147-B2 Chemoenzymatic synthesis of trehalose analogues CENTRAL MICHIGAN UNIVERSITY 2024-01-23 US claimed
US-20210108247-A1 CHEMOENZYMATIC SYNTHESIS OF TREHALOSE ANALOGUES CENTRAL MICHIGAN UNIVERSITY 2021-04-15 US claimed
CN-109371079-B A kind of biological synthesis method of uridine diphosphoglucose and uridine diphosphate glucuronate 安徽禾庚生物技术有限公司 2019-09-06 CN claimed
CN-109371079-A A kind of biological synthesis method of uridine diphosphoglucose and uridine diphosphate glucuronate 安徽禾庚生物技术有限公司 2019-02-22 CN claimed
US-20180119196-A1 Chemoenzymatic Synthesis of Trehalose Analogs CENTRAL MICHIGAN UNIVERSITY 2018-05-03 US claimed
US-9873905-B2 Chemoenzymatic synthesis of trehalose analogs CENTRAL MICHIGAN UNIVERSITY (US) 2018-01-23 US claimed
CN-106916776-A The engineering bacteria and construction method of overexpression phosphoglucomutase gene and UDPglucose pyrophosphorylase gene 厦门大学 2017-07-04 CN claimed
CN-106701802-A Overexpressed UGPase (Uridine Diphosphoglucose Pyrophosphorylase) gene as well as construction method and purification method for recombinant escherichia coli thereof 宁波大学 2017-05-24 CN claimed
EP-2742142-B1 RECOMBINANT PRODUCTION OF STEVIOL GLYCOSIDES EVOLVA SA (CH) 2016-06-01 EP claimed
US-20150252402-A1 Chemoenzymatic Synthesis of Trehalose Analogs CENTRAL MICHIGAN UNIVERSITY 2015-09-10 US claimed
EP-0635051-B1 INCREASING THE TREHALOSE CONTENT OF ORGANISMS BY TRANSFORMING THEM WITH COMBINATIONS OF THE STRUCTURAL GENES FOR TREHALOSE SYNTHASE BTG INT LTD (GB) 2004-06-23 EP claimed
US-20040082593-A1 Infusion of ciprofloxacin having reduced acid content and being stable in storage FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2004-04-29 US claimed
EP-1356072-A2 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ) MICHIGAN STATE UNIVERSITY (US) 2003-10-29 EP claimed
WO-2002048706-A2 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ) MICHIGAN STATE UNIVERSITY (US) 2002-06-20 WO claimed
EP-0763132-B1 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB INC (US) 2001-01-24 EP claimed
US-6022865-A Stable aqueous solution having high concentrations of calcium and phosphate ions and solid complex UNIVERSITY OF CINCINNATI (US) 2000-02-08 US claimed
WO-2000003006-A1 SUCROSE BIOSYNTHESIS GENES AND USES THEREFOR COMMONWEALTH SCIENTIFIC INDUSTRIAL AND RESEARCH ORGANISATION (AU) 2000-01-20 WO claimed
EP-0925367-A2 A PROCESS OF INCREASING PLANT GROWTH AND YIELD AND MODIFIYING CELLULOSE PRODUCTION IN PLANTS B.C. Research Inc. (CA) 1999-06-30 EP claimed
WO-1998011240-A2 A PROCESS OF INCREASING PLANT GROWTH AND YIELD AND MODIFIYING CELLULOSE PRODUCTION IN PLANTS B.C. RESEARCH INC. (CA) 1998-03-19 WO claimed
WO-1995020673-A1 ORGANO-PHOSPHORUS COMPOUNDS AS ACTIVATORS OF GAMMA DELTA T CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 1995-08-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210108247-A1 CHEMOENZYMATIC SYNTHESIS OF TREHALOSE ANALOGUES TREH, TALDO1, TKT LMNA 3638/4885L3MBTL1 2699/4885MPI 24/4885
US-11879147-B2 Chemoenzymatic synthesis of trehalose analogues TREH, TALDO1, TKT LMNA 3638/4885L3MBTL1 2699/4885MPI 24/4885
US-20180119196-A1 Chemoenzymatic Synthesis of Trehalose Analogs TREH, TALDO1, TKT LMNA 3565/4885L3MBTL1 2535/4885MPI 19/4885
US-20150252402-A1 Chemoenzymatic Synthesis of Trehalose Analogs TREH, TALDO1, TKT LMNA 3565/4885L3MBTL1 2535/4885MPI 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.