Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348422 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1PPARG | |
| SCHEMBL5363825 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1PPARG | |
| SCHEMBL5365046 | 0.82 | PPARG (0.44) | ALDH1A1MEN1KMT2AL3MBTL1PPARG | |
| SCHEMBL5363821 | 0.82 | PPARG (0.44) | ALDH1A1MEN1KMT2AL3MBTL1PPARG | |
| SCHEMBL5348417 | 0.82 | PPARG (0.44) | ALDH1A1MEN1KMT2AL3MBTL1PPARG | |
| SCHEMBL1628549 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL1231134 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL1231133 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL5348847 | 0.80 | CACNA1B (0.44) | ALDH1A1L3MBTL1PPARGPPARAMAPT | |
| SCHEMBL5363836 | 0.77 | L3MBTL1 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | ALDH1A1 3065/4885MEN1 2633/4885KMT2A 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.