SCHEMBL536532

SCHEMBL536532

O=C(O)CC(O)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 2/20 0.47
HCAR2 Q8TDS4 1/20 0.47
CPA1 P15085 2/20 0.46
CASP1 P29466 2/20 0.46
CPB1 P15086 1/20 0.46
CPA3 P15088 1/20 0.46
CPB2 Q96IY4 1/20 0.46
LTA4H P09960 1/20 0.46
LAP3 P28838 1/20 0.46
HTT P42858 1/20 0.45
MMP12 P39900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133837 1.00 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL10357917 1.00 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
Glycolic Acid SCHEMBL537038 0.95 ALDH1A1 (0.49) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL5400331 0.89 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL673677 0.87 ALDH1A1 (0.59) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL16399030 0.87 ALDH1A1 (0.59) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL19846216 0.86 ALDH1A1 (0.59) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL11128611 0.84 ALDH1A1 (0.49) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL9809390 0.84 ALDH1A1 (0.49) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL11128607 0.84 ALDH1A1 (0.49) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777417-A Star-shaped beta-polymalic acid and preparation method and application thereof 中国人民解放军空军军医大学 2024-03-29 CN claimed
CN-114015659-B Purification method of rabies vaccine 江苏金迪克生物技术股份有限公司 2024-02-27 CN claimed
CN-117089060-A Initiation/catalyst, preparation method and application thereof, polylactic acid-polymalic acid, preparation method and application thereof 西北工业大学 2023-11-21 CN claimed
CN-107759778-B Preparation and application of polymalic acid and high-crystallinity poly (benzyl malate) 中国人民解放军第四军医大学 2020-04-28 CN claimed
CN-107759778-A The preparation and application of a kind of polymalic acid and the high polymalic acid benzyl ester of crystallinity 中国人民解放军第四军医大学 2018-03-06 CN claimed
CN-103635497-A Method for polymerizing resin casting for use as epoxy acrylic optical lens and resin composition containing internal releasing agent for use in epoxy acrylic optical lens KOC SOLUTION CO LTD 2014-03-12 CN claimed
CN-117659225-B Cationic amphiphilic chitosan quaternary ammonium salt and preparation method and application thereof 安徽农业大学 2024-06-07 CN disclosed
CN-117777417-A Star-shaped beta-polymalic acid and preparation method and application thereof 中国人民解放军空军军医大学 2024-03-29 CN disclosed
CN-117659225-A Cationic amphiphilic chitosan quaternary ammonium salt and preparation method and application thereof 安徽农业大学 2024-03-08 CN disclosed
CN-114015659-B Purification method of rabies vaccine 江苏金迪克生物技术股份有限公司 2024-02-27 CN disclosed
CN-117377665-A PARP7 inhibitor and application thereof 北京华森英诺生物科技有限公司 2024-01-09 CN disclosed
WO-2023240379-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF 南京医工医药技术有限公司 2023-12-21 WO disclosed
WO-2023240156-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
US-5118528-A PROCESS FOR THE PREPARATION OF DISPERSIBLE COLLOIDAL SYSTEMS OF A SUBSTANCE IN THE FORM OF NANOPARTICLES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1992-06-02 US disclosed
US-5049322-A Process for the preparaton of dispersible colloidal systems of a substance in the form of nanocapsules CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 1991-09-17 US disclosed
EP-0191491-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP disclosed
US-4992544-A Intermediates for b-lactam antibiotics and b-lactamase inhibitor UNIVERSITY OF NOTRE DAME DU LAC (US) 1991-02-12 US disclosed
EP-0341602-A2 Renin-inhibiting functionalized peptidyl aminodiols and - triols ABBOTT LABORATORIES (US) 1989-11-15 EP disclosed
US-4859576-A Silver halide photographic material comprising a protective layer containing a polyoxyethylene surface active agent FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed
EP-0191491-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-08-20 EP disclosed