Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 9/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536532 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL1133837 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL10357917 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| Glycolic Acid SCHEMBL537038 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL16399030 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL673677 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL5400343 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL5400346 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL7631946 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1CASP1SLC6A2 | |
| SCHEMBL20043008 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169803-B2 | N-substituted prodrugs of fluorooxindoles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050203089-A1 | N-substituted prodrugs of fluorooxindoles | BRISTOL-MYERS SQUIBB COMPANY | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203089-A1 | N-substituted prodrugs of fluorooxindoles | KCNA5, KCNQ5, KCNQ2 | ALDH1A1 2272/4885MAPK1 2122/4885L3MBTL1 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.