Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425360 | 1.00 | GRIN2B (0.47) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL5359420 | 0.90 | GRIN2B (0.46) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL5378232 | 0.89 | GRIN2B (0.48) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL14425365 | 0.89 | GRIN2B (0.48) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL14425383 | 0.89 | GRIN2B (0.47) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL5360990 | 0.89 | GRIN2B (0.47) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL14425370 | 0.87 | ENPP2 (0.42) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL5360981 | 0.87 | ENPP2 (0.42) | GRIN2BALDH1A1LMNAENPP2HPGD | |
| SCHEMBL5365495 | 0.87 | ENPP2 (0.40) | ENPP2HPGDMEN1KMT2ANAMPT | |
| SCHEMBL14425317 | 0.86 | MEN1 (0.50) | GRIN2BALDH1A1LMNAENPP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |