Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358762 | 0.82 | CYP11B2 (0.40) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5354656 | 0.80 | AR (0.40) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5365214 | 0.80 | CYP11B2 (0.43) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL6889076 | 0.79 | AR (0.51) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5357164 | 0.78 | CYP11B2 (0.39) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5368138 | 0.78 | CYP11B2 (0.38) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5364131 | 0.75 | CYP11B2 (0.40) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL5362436 | 0.75 | CYP11B2 (0.40) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL14348315 | 0.75 | CYP11B2 (0.40) | CYP11B2ARLMNAMAPTKDM4E | |
| SCHEMBL13362172 | 0.74 | CYP11B2 (0.39) | CYP11B2ARLMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |