SCHEMBL536578

SCHEMBL536578

Sc1cccc2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 5/20 1.00
COPS5 Q92905 5/20 1.00
LMNA P02545 4/20 0.61
KDM4E B2RXH2 3/20 0.61
MMP2 P08253 2/20 0.61
TSHR P16473 2/20 0.61
MAPT P10636 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
HSP90AA1 P07900 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
MMP9 P14780 1/20 0.61
ALOX15 P16050 1/20 0.61
NFKB1 P19838 1/20 0.61
MMP8 P22894 1/20 0.61
CCR1 P32246 1/20 0.61
THPO P40225 1/20 0.61
MTOR P42345 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30079755 1.00 PSMD14 (1.00) PSMD14COPS5LMNAKDM4EMMP2
Hydrochloric Acid SCHEMBL30430691 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL7333832 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL7431585 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL1822441 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
Hydrochloric Acid SCHEMBL23648281 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
Hydrochloric Acid SCHEMBL1333579 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL4819240 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL9221538 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2
SCHEMBL27629030 0.98 PSMD14 (0.95) PSMD14COPS5LMNAKDM4EMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241800-B1 ABSORBABLE IMPLANTABLE MEDICAL DEVICE MADE OF IRON-BASED ALLOY BIOTYX MEDICAL SHENZHEN CO LTD (CN) 2025-08-27 EP claimed
US-12208378-B1 1,4-divinylphenylene-bridged diruthenium complex bearing two Ru(CO) (PiPr3)2 moieties with 8-mercaptoquinolato co-ligand as an organic catalyst King Faisal University (SA) 2025-01-28 US claimed
CN-118703196-A Light-activated microsphere and preparation method thereof 深圳市帝迈生物技术有限公司 2024-09-27 CN claimed
WO-2024129619-A9 STAT3 INHIBITORS FOR USE IN THE TREATMENT OF NON-VIRAL LIVER CANCER TVARDI THERAPEUTICS, INC. (US) 2024-07-18 WO claimed
WO-2024129619-A1 STAT3 INHIBITORS FOR USE IN THE TREATMENT OF NON-VIRAL LIVER CANCER TVARDI THERAPEUTICS, INC. (US) 2024-06-20 WO claimed
US-11986810-B1 Selective reduction catalyst of α,β-unsaturated ketone using electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(8-mercaptoquinolato(PiPr3)2 moieties King Faisal University (SA) 2024-05-21 US claimed
CN-116999680-A Drug shock wave balloon catheter 深圳市赛禾医疗技术有限公司 2023-11-07 CN claimed
EP-4241800-A2 ABSORBABLE IMPLANTABLE MEDICAL DEVICE MADE OF IRON-BASED ALLOY Biotyx Medical (Shenzhen) Co., Ltd. (CN) 2023-09-13 EP claimed
WO-2023168420-A1 COMBINATIONS OF STAT-INHIBITORS AND IMMUNE CHECKPOINT INHIBITORS FOR THE TREATMENT AND/OR MANAGEMENT OF CANCER TVARDI THERAPEUTICS, INC. (US) 2023-09-07 WO claimed
US-20230274946-A1 ETCHING COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2023-08-31 US claimed
CN-1135420-A Anti-counterfeiting fluorescent pressure-sensitive carbon paper and manufacturing method thereof GEDE ANTIFAKE TECH CO NANKAI U (CN) 1996-11-13 CN claimed
CN-1135421-A Anti-counterfeiting fluorescent pressure-sensitive carbon paper capable of generating invisible carbon writing and manufacturing method thereof GEDE ANTI FAKE TECH CO NANKAI (CN) 1996-11-13 CN claimed
CN-1132696-A Printing process of anti-forgery mark GEDE ANTI FORGERY TECHNOLOGY C (CN) 1996-10-09 CN claimed
CN-1117927-A Fluorescent anti-fake mark and its making method XINTONG SCIENCE & TECHNOLOGY C (CN) 1996-03-06 CN claimed
US-5496491-A FOR PHOTORESISTS, AMINE SALT REACTION PRODUCT ASHLAND OIL COMPANY (US) 1996-03-05 US claimed
EP-0661324-A1 Hight-initiated cationic curable epoxyresin compositions and their use THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1995-07-05 EP claimed
EP-0403524-B1 PREPARATION OF NITRURO COMPOUNDS USABLE AS RADIO-PHARMACEUTICAL PRODUCTS CIS BIO INTERNATIONAL (FR) 1993-02-10 EP claimed
EP-0403524-A1 PREPARATION OF NITRURO COMPOUNDS USABLE AS RADIO-PHARMACEUTICAL PRODUCTS. CIS BIO INT (FR) 1990-12-27 EP claimed
WO-1989008657-A2 PREPARATION OF NITRURO COMPOUNDS USABLE AS RADIO-PHARMACEUTICAL PRODUCTS CIS BIO INTERNATONAL (FR) 1989-09-21 WO claimed
US-3982999-A LEUKEMIA KHARASCH JEROME A 1976-09-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12208378-B1 1,4-divinylphenylene-bridged diruthenium complex bearing two Ru(CO) (PiPr3)2 moieties with 8-mercaptoquinolato co-ligand as an organic catalyst PIP4K2A, PIP4K2B, PIP4K2C PSMD14 1136/4885COPS5 483/4885LMNA 4841/4885
US-11986810-B1 Selective reduction catalyst of α,β-unsaturated ketone using electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(8-mercaptoquinolato(PiPr3)2 moieties PI4K2B, DHCR24, PI4K2A PSMD14 1814/4885COPS5 2107/4885LMNA 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.