Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347747 | 0.80 | MAPT (0.39) | ELANEMAPTTDP1KDM4EHPGD | |
| SCHEMBL5362630 | 0.79 | AR (0.41) | MAPTKDM4ELMNASMN1; SMN2CYP11B2 | |
| SCHEMBL5357688 | 0.79 | CYP11B2 (0.36) | MAPTKDM4ELMNASMN1; SMN2CYP11B2 | |
| SCHEMBL14348314 | 0.77 | AR (0.42) | MAPTKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL5362436 | 0.76 | CYP11B2 (0.40) | MAPTKDM4ELMNASMN1; SMN2CYP11B2 | |
| SCHEMBL4917436 | 0.74 | TSHR (0.48) | MAPTTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL5487110 | 0.74 | KMT2A (0.40) | ELANEMAPTTDP1KDM4EHPGD | |
| SCHEMBL4914037 | 0.74 | AR (0.50) | MAPTTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL5353839 | 0.73 | KMT2A (0.39) | ELANEMAPTTDP1KDM4EHPGD | |
| SCHEMBL13362172 | 0.73 | CYP11B2 (0.39) | MAPTKDM4ELMNASMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |