Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353839 | 0.87 | KMT2A (0.39) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL5359996 | 0.81 | AR (0.39) | CYP11B2ARFNTAFNTB | |
| SCHEMBL3081244 | 0.77 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL5365877 | 0.74 | ELANE (0.40) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL4917896 | 0.71 | AR (0.49) | ALDH1A1GAALMNAMAPTTDP1 | |
| SCHEMBL13362172 | 0.71 | CYP11B2 (0.39) | KMT2AMEN1LMNAMAPTCYP11B2 | |
| SCHEMBL14347747 | 0.70 | MAPT (0.39) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL20640817 | 0.70 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL5366156 | 0.68 | AR (0.37) | CYP11B2AR | |
| SCHEMBL3074166 | 0.68 | AR (0.39) | KMT2AALDH1A1MEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |