SCHEMBL5366018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11102266	0.83	RXFP1 (0.37)	HRH4MAPTMEN1KMT2AKDM4E
	SCHEMBL31015696	0.75	TRPA1 (0.45)	HRH4TRPA1SIGMAR1NOS3NOS1
	SCHEMBL561485	0.75	TRPA1 (0.45)	HRH4TRPA1SIGMAR1NOS3NOS1
	SCHEMBL30145150	0.74	TRPA1 (0.46)	HRH4TRPA1IDO1MAPTLMNA
	SCHEMBL13961627	0.72	HRH4 (0.46)	HRH4TRPA1MAOASIGMAR1PLK4
	SCHEMBL85967	0.72	HRH4 (0.54)	HRH4TRPA1MAOASIGMAR1PLK4
	SCHEMBL8207110	0.72	HRH4 (0.50)	HRH4TRPA1MAOASIGMAR1PLK4
	SCHEMBL1772613	0.72	HRH4 (0.50)	HRH4TRPA1MAOASIGMAR1PLK4
	SCHEMBL14507199	0.69	IDO1 (0.50)	HRH4TRPA1MAOASIGMAR1PLK4
	SCHEMBL85780	0.69	TRPA1 (0.37)	HRH4TRPA1SIGMAR1HRH1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.