Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507199 | 0.82 | IDO1 (0.50) | TRPA1RARARARBRXRARXRB | |
| SCHEMBL30145190 | 0.80 | HRH4 (0.47) | TRPA1RARARARBRXRARXRB | |
| SCHEMBL30145076 | 0.77 | RARA (0.46) | RARARARBRXRARXRBRXRG | |
| SCHEMBL14507248 | 0.75 | HDAC3 (0.56) | TRPA1RARARARBRXRARXRB | |
| SCHEMBL5366018 | 0.74 | HRH4 (0.46) | TRPA1HRH4LMNAMAPTIDO1 | |
| SCHEMBL7701030 | 0.73 | NOS3 (0.45) | LAP3MAOBLMNAMAPTIDO1 | |
| SCHEMBL28246117 | 0.72 | PDK2 (0.50) | TRPA1LAP3MAOBLMNAMAPT | |
| SCHEMBL30145240 | 0.71 | GSK3A (0.46) | RARARARBRXRARXRBRXRG | |
| SCHEMBL29234139 | 0.70 | OPRD1 (0.37) | TRPA1MAOBIDO1CYP11B2TSHR | |
| SCHEMBL27740845 | 0.69 | LAP3 (0.51) | HRH4LAP3MAOBCYP11B2FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072500-B | Synthetic method of dibenzo [ b, e ] azepine compound | 淮北师范大学 | 2023-01-20 | — | — | CN | disclosed |