SCHEMBL536613

SCHEMBL536613

CC(=O)OC(C)(C)CC(C)(C)CC(C)(C)OC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726281 0.93 GAA (0.41) GAA
SCHEMBL10456471 0.89 GAA (0.50) GAAALDH1A1LMNAHSD17B10TSHR
SCHEMBL16254850 0.88 GAA (0.41) GAAALDH1A1LMNAHSD17B10
SCHEMBL24992192 0.86 GAA (0.40) GAA
SCHEMBL13286223 0.86 GAA (0.40) GAA
SCHEMBL43112 0.84 GAA (0.46) GAAALDH1A1LMNAHSD17B10TSHR
SCHEMBL9465473 0.82 GAA (0.44) GAAALDH1A1LMNAHSD17B10TSHR
SCHEMBL18250840 0.80 GAA (0.43) GAA
SCHEMBL10046620 0.80 GAA (0.43) GAATSHR
SCHEMBL19275048 0.80 GAA (0.48) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544238-B2 Methods of preparing functionalized polyolefins CHEVRON ORONITE COMPANY LLC (US) 2020-01-28 US disclosed
EP-2925804-B1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE CO (US) 2019-02-20 EP disclosed
EP-2414432-B1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE CO (US) 2017-05-31 EP disclosed
US-20170096502-A1 METHODS OF PREPARING FUNCTIONALIZED POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2017-04-06 US disclosed
US-9315595-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-04-19 US disclosed
US-9243203-B2 Copolymers of polyaminopolyolefins and polyanhydrides and methods of their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-01-26 US disclosed
CN-104812804-A Copolymers of polyaminopolyolefins and polyanhydrides CHEVRON ORONITE CO 2015-07-29 CN disclosed
CN-102356114-B Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE CO 2014-06-25 CN disclosed
US-20140155308-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES AND METHODS OF THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2014-06-05 US disclosed
US-20140031497-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2014-01-30 US disclosed
US-8552122-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-10-08 US disclosed
EP-2414432-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION Chevron Oronite Company LLC (US) 2012-02-08 EP disclosed
WO-2010117619-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2010-10-14 WO disclosed
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-09-30 US disclosed
US-5248746-A Cationic polymerization, molecular weight control NIPPON ZEON CO., LTD. (JP) 1993-09-28 US disclosed
EP-0451679-A2 Method of producing polymers NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0397081-A2 Process for preparation of polymer NIPPON ZEON CO., LTD. (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION TERT, TELO2, TSPO GAA 3584/4885ALDH1A1 3744/4885LMNA 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.