SCHEMBL5366433

SCHEMBL5366433

O=P(O)(O)Oc1c[nH]c2cccc(Cl)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.52
HTR2A P28223 3/20 0.50
HTR1A P08908 1/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
GPR84 Q9NQS5 1/20 0.46
INPPL1 O15357 4/20 0.43
INPP5A Q14642 4/20 0.43
INPP5B P32019 2/20 0.43
IDO1 P14902 1/20 0.38
AKT1 P31749 1/20 0.38
SLC6A4 P31645 1/20 0.38
SRC P12931 3/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
PDE3A Q14432 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ERCC5 P28715 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617466 0.87 NR4A2 (0.51) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL365787 0.85 NR4A2 (0.48) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL6513067 0.79 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL23488 0.77 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL29356973 0.77 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
Phosphoric Acid SCHEMBL8156858 0.76 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL5058499 0.76 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL31324009 0.76 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
Ammonia Solution, Strong SCHEMBL20492883 0.76 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B
SCHEMBL17668115 0.76 HTR2A (0.40) NR4A2HTR2AHTR1AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143231-B Pharmaceutical composition comprising stem cell exosomes and method for preparing the same 赛洱生命科学(哈尔滨)有限公司 2025-01-14 CN disclosed
CN-117203528-A GDF15 marker panel for early detection of sepsis 豪夫迈·罗氏有限公司 2023-12-08 CN disclosed
CN-117143231-A Pharmaceutical composition comprising stem cell exosomes and method for preparing the same 济南姚盛成达生物科技有限公司 2023-12-01 CN disclosed
CN-117143243-A Preparation method and pharmaceutical application of stem cell exosome 济南姚盛成达生物科技有限公司 2023-12-01 CN disclosed
EP-3121282-B1 NOVEL SAMDORI-2 GENE AND USE THEREOF NEUROMIND CO LTD (KR) 2019-11-06 EP disclosed
US-10364275-B2 Methods for treating inflammatory responses or diseases caused by inflammation using ApoA-I binding protein (APOA1BP) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-30 US disclosed
US-20170037101-A1 Novel Brain Chemokine Samdori and Use Thereof GHBIO INC. (KR) 2017-02-09 US disclosed
EP-3121282-A1 NOVEL SAMDORI-2 GENE AND USE THEREOF GHBIO INC. (KR) 2017-01-25 EP disclosed
CN-104722342-B Slip chip device and method 芝加哥大学 2017-01-11 CN disclosed
CN-105899532-A Fusion constructs of FAB-effector moieties of antiserum albumin and methods of making same 艾普丽尔生物有限公司 2016-08-24 CN disclosed
EP-0724590-A1 $i(PLASMODIUM FALCIPARUM) RIBONUCLEOTIDE REDUCTASE, ENCODING DNA, AND INHIBITORS UNIVERSITY OF PENNSYLVANIA (US) 1996-08-07 EP disclosed
US-5459063-A Antimalarial agents THE UNIVERSITY OF PENNSYLVANIA (US) 1995-10-17 US disclosed
WO-1995010526-A1 PLASMODIUM FALCIPARUM RIBONUCLEOTIDE REDUCTASE, ENCODING DNA, AND INHIBITORS THE UNIVERSITY OF PENNSYLVANIA (US) 1995-04-20 WO disclosed
EP-0324468-A2 A highly specific method for detecting nucleic acids in solution Roche Diagnostics GmbH (DE) 1989-07-19 EP disclosed
EP-0198413-B1 RAPID ASSAY PROCESSOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-12 EP disclosed
US-4806313-A Rapid assay processor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-21 US disclosed
EP-0303155-A2 Method to identify nucleic-acid sequences MERCK PATENT GmbH (DE) 1989-02-15 EP disclosed
US-4775635-A Rapid assay processor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-04 US disclosed
US-4753775-A Rapid assay processor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-28 US disclosed
EP-0198413-A2 Rapid assay processor E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-22 EP disclosed