Quinoxaline

Quinoxaline

SCHEMBL5366555

c1ccc2[nH]ccc2c1.c1ccc2nccnc2c1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.68
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
ITGB2 P05107 1/20 0.68
ICAM1 P05362 1/20 0.68
ITGAL P20701 1/20 0.68
CA4 P22748 1/20 0.68
CA6 P23280 1/20 0.68
AHR P35869 1/20 0.68
ADK P55263 1/20 0.68
ALDH1A1 P00352 5/20 0.45
AXL P30530 1/20 0.44
NUDT1 P36639 1/20 0.44
MAPK1 P28482 2/20 0.42
TGFBR1 P36897 1/20 0.41
NPC1 O15118 4/20 0.40
PDE10A Q9Y233 1/20 0.39
PSMD14 O00487 1/20 0.39
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28816675 0.89 ALDH1A1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Quinoline SCHEMBL28292512 0.89 ALDH1A1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Quinoline SCHEMBL843861 0.89 ALDH1A1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Quinoline SCHEMBL28073739 0.89 ALDH1A1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Quinoline SCHEMBL27739225 0.87 ALDH1A1 (0.61) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL6702023 0.83 AHR (0.90) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL7026553 0.83 AHR (0.90) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL30463845 0.82
Indole SCHEMBL30250492 0.82
Indole SCHEMBL29352896 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110283177-A The method that one-step method prepares indoles quinoxaline compound 华南师范大学 2019-09-27 CN claimed
CN-1151790-C Agent for transplantation ������J��I���׵²����� 2004-06-02 CN claimed
CN-1341023-A Agent for transplantation LEIF J I LUNDBLAD (SE) 2002-03-20 CN claimed
CN-117865962-A Novel indole diketone and indole quinoxaline derivative fluorescent compound, and preparation method and application thereof 江南大学 2024-04-12 CN disclosed
CN-117865962-A Novel indole diketone and indole quinoxaline derivative fluorescent compound, and preparation method and application thereof 江南大学 2024-04-12 CN disclosed
CN-117865962-A Novel indole diketone and indole quinoxaline derivative fluorescent compound, and preparation method and application thereof 江南大学 2024-04-12 CN disclosed
CN-110563938-B Polyether copolymer, crosslinkable polyether copolymer composition, electrolyte, and composite 日本瑞翁株式会社 2022-07-22 CN disclosed
CN-109860430-B Hole-transport exciton-blocking organic material and application thereof 江西冠能光电材料有限公司 2021-08-06 CN disclosed
CN-110563938-A Polyether copolymer, crosslinkable polyether copolymer composition, electrolyte, and composite 日本瑞翁株式会社 2019-12-13 CN disclosed
CN-110283177-A The method that one-step method prepares indoles quinoxaline compound 华南师范大学 2019-09-27 CN disclosed
CN-110283177-A The method that one-step method prepares indoles quinoxaline compound 华南师范大学 2019-09-27 CN disclosed
CN-103901750-B9 Image forming apparatus, process cartridge and image forming method 株式会社理光 2016-10-19 CN disclosed
CN-103901750-B Image processing system, cartridge processing and image forming method 株式会社理光 2016-08-31 CN disclosed
CN-105061432-A 6H-indole[2,3-b] quinoxaline derivatives, pharmaceutical composition as well as preparation and application of 6H-indole[2,3-b] quinoxaline derivatives UNIV HEBEI 2015-11-18 CN disclosed
CN-104066768-A Resin composition for display substrates NISSAN CHEMICAL IND LTD 2014-09-24 CN disclosed
CN-103901750-A Image forming apparatus, process cartridge, and image forming method RICOH CO LTD 2014-07-02 CN disclosed
CN-101446779-A Electrophotographic photoconductor and electrophotographic apparatus RICOH KK (JP) 2009-06-03 CN disclosed
JP-2007099641-A INDOLEQUINOXALINE COMPOUND, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITION USING THE SAME TSUMURA & CO 2007-04-19 JP disclosed
CN-1151790-C Agent for transplantation ������J��I���׵²����� 2004-06-02 CN disclosed
CN-1341023-A Agent for transplantation LEIF J I LUNDBLAD (SE) 2002-03-20 CN disclosed