SCHEMBL5367055

SCHEMBL5367055

CC(=O)Oc1cc(OC(C)=O)c2c(c1)OC(c1ccc(O)c(OC(C)=O)c1)C(OC(C)=O)C2

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.84
ALDH1A1 P00352 1/20 0.84
MAPK1 P28482 1/20 0.84
SMN1; SMN2 Q16637 1/20 0.84
ABCB1 P08183 4/20 0.64
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPT P10636 2/20 0.56
STING1 Q86WV6 3/20 0.56
GABRA1 P14867 3/20 0.49
GABRB2 P47870 3/20 0.49
MMP2 P08253 2/20 0.46
MMP14 P50281 2/20 0.46
BCL2 P10415 2/20 0.46
APP P05067 1/20 0.46
PKM P14618 1/20 0.46
BACE1 P56817 1/20 0.46
SYNJ2 O15056 1/20 0.46
ADAMTS4 O75173 1/20 0.46
SLCO2B1 O94956 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(+/-)-Pentaacetylcatechin SCHEMBL719420 0.92 ALDH1A1 (1.00) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
Epicatechin Pentaacetate SCHEMBL14691288 0.92 ALDH1A1 (1.00) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
(+/-)-Pentaacetylcatechin SCHEMBL14701425 0.92 ALDH1A1 (1.00) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
Catechin Pentaacetate SCHEMBL719419 0.92 ALDH1A1 (1.00) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
SCHEMBL28800434 0.86 CYP3A4 (0.69) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
SCHEMBL27903202 0.86 CYP3A4 (0.69) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
SCHEMBL23135645 0.86 ABCB1 (0.84) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1
SCHEMBL27886442 0.84 CYP3A4 (0.66) CYP3A4ALDH1A1MAPK1SMN1; SMN2MEN1
SCHEMBL27886444 0.84 CYP3A4 (0.66) CYP3A4ALDH1A1MAPK1SMN1; SMN2MEN1
SCHEMBL4671149 0.82 ALDH1A1 (0.81) CYP3A4ALDH1A1MAPK1SMN1; SMN2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007041891-A1 METHODS OF SEPARATING CATECHINS FROM GREEN TEA LEAVES THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2007-04-19 WO disclosed