Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (+/-)-Pentaacetylcatechin SCHEMBL719420 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| Epicatechin Pentaacetate SCHEMBL14691288 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| Catechin Pentaacetate SCHEMBL719419 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL5367055 | 0.92 | CYP3A4 (0.84) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL5109161 | 0.90 | ALDH1A1 (0.81) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL4671149 | 0.90 | ALDH1A1 (0.81) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL23135645 | 0.88 | ABCB1 (0.84) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL6702376 | 0.87 | CYP3A4 (0.77) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL14701484 | 0.87 | CYP3A4 (0.77) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 | |
| SCHEMBL16838244 | 0.86 | ALDH1A1 (0.75) | ALDH1A1CYP3A4MAPK1SMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187448-B2 | Flavonoid compounds | CARDERO THERAPEUTICS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-9187448-B2 | Flavonoid compounds | CARDERO THERAPEUTICS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140256741-A1 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256741-A1 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| WO-2013022846-A2 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256741-A1 | FLAVONOID COMPOUNDS | FIS1, TFAM, MFN2 | ALDH1A1 1984/4885CYP3A4 3740/4885MAPK1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.