Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931663 | 0.89 | MAPK1 (0.43) | MAPK1SMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL1931669 | 0.88 | MAPK1 (0.42) | MAPK1RAB9ANPC1GAAMAPT | |
| SCHEMBL1931559 | 0.77 | ALDH1A1 (0.40) | MAPK1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL1931390 | 0.76 | ALDH1A1 (0.40) | MAPK1SMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL1930915 | 0.75 | ALDH1A1 (0.41) | MAPK1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL1930678 | 0.74 | ALDH1A1 (0.40) | MAPK1SMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL1935497 | 0.74 | MAPK1 (0.60) | MAPK1SMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL1930756 | 0.74 | RORC (0.45) | MAPK1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL1931173 | 0.73 | ALDH1A1 (0.39) | MAPK1SMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL1932041 | 0.72 | RORC (0.41) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861403-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097625-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-AVENTIS (FR) | 2006-09-21 | — | — | WO | disclosed |