SCHEMBL5367323

SCHEMBL5367323

O=C(NCc1ccccc1)c1ccc(N2CCCN(C(=O)c3ccccc3Cl)C2)nn1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 12/20 0.59
SCD O00767 8/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5312647 0.86 SCD (0.80) DCTPP1SCD
SCHEMBL5309321 0.84 DCTPP1 (0.54) DCTPP1SCD
SCHEMBL5311618 0.84 ALDH1A1 (0.57) SCD
SCHEMBL5309412 0.83 SCD (0.55) DCTPP1SCD
SCHEMBL5309024 0.81 DCTPP1 (0.51) DCTPP1SCD
SCHEMBL5306130 0.80 DCTPP1 (0.49) DCTPP1SCD
SCHEMBL5310827 0.80 SCD (0.70) DCTPP1SCD
SCHEMBL5309139 0.80 SCD (0.70) DCTPP1SCD
SCHEMBL28111329 0.79 DCTPP1 (0.65) DCTPP1SCD
SCHEMBL5306153 0.79 DCTPP1 (0.49) DCTPP1SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046867-A2 PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2007-04-26 WO disclosed