Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356119 | 0.93 | HTR6 (0.78) | HTR6USP2ALDH1A1LMNAHTT | |
| SCHEMBL5366229 | 0.83 | HTR6 (1.00) | HTR6USP2ALDH1A1LMNAHTT | |
| SCHEMBL5369827 | 0.81 | HTR6 (0.81) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5444888 | 0.78 | HTR6 (0.76) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5361093 | 0.78 | HTR6 (0.68) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5359580 | 0.77 | HTR6 (0.83) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5356214 | 0.77 | HTR6 (0.75) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5361105 | 0.77 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5354772 | 0.75 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5358289 | 0.75 | HTR6 (0.66) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138611-A1 | 3-(HETEROCYCLYL)-N-(ARYLSULFONYL)INDOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138611-A1 | 3-(HETEROCYCLYL)-N-(ARYLSULFONYL)INDOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-12-06 | — | — | WO | disclosed |