Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.71 |
| ▸ | LTA4H | P09960 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183713 | 0.91 | LTA4H (0.64) | HTR2ALTA4HGAAALDH1A1PKM | |
| SCHEMBL5365328 | 0.91 | ALDH1A1 (0.64) | HTR2ALTA4HGAAALDH1A1SIGMAR1 | |
| SCHEMBL5368435 | 0.90 | CYP1A2 (0.65) | HTR2ALTA4HGAAALDH1A1SIGMAR1 | |
| SCHEMBL5175617 | 0.87 | LTA4H (0.77) | HTR2ALTA4HSIGMAR1 | |
| SCHEMBL1519356 | 0.87 | HTR2A (0.75) | HTR2ALTA4HSIGMAR1ACHECCR3 | |
| SCHEMBL27300983 | 0.87 | HTR2A (0.75) | HTR2ASIGMAR1ACHECCR3OPRM1 | |
| SCHEMBL12642700 | 0.86 | HTR2A (0.55) | HTR2ALTA4HGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1405913 | 0.86 | HTR2A (0.73) | HTR2ALTA4HSIGMAR1ACHECCR3 | |
| SCHEMBL4703785 | 0.85 | TDP1 (0.57) | HTR2ALTA4HGAAALDH1A1 | |
| SCHEMBL4069863 | 0.85 | HTR2A (0.72) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| CN-119497709-A | Pyrimidine derivatives | ASKA 制药株式会社 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1390034-A4 | N-SUBSTITUTED NONARYL-HETEROCYCLO AMIDYL NMDA/NR2B ANTAGONISTS | MERCK & CO INC (US) | 2005-07-13 | — | — | EP | disclosed |
| EP-1390034-A1 | N-SUBSTITUTED NONARYL-HETEROCYCLO AMIDYL NMDA/NR2B ANTAGONISTS | Merck & Co., Inc. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002080928-A1 | N-SUBSTITUTED NONARYL-HETEROCYCLO AMIDYL NMDA/NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2002-10-17 | — | — | WO | disclosed |