Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 13/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687782 | 0.81 | P2RX4 (0.44) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL5367306 | 0.76 | LMNA (0.42) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL3691734 | 0.76 | LMNA (0.55) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL1248214 | 0.76 | P2RX4 (0.46) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL10653232 | 0.73 | LMNA (0.39) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL1246144 | 0.72 | LMNA (0.39) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL6312853 | 0.70 | LMNA (0.41) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL5172363 | 0.69 | BCHE (0.46) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL8672568 | 0.69 | P2RX4 (0.46) | P2RX4MAPK1LMNATSHRSCN4A | |
| SCHEMBL3732224 | 0.69 | P2RX4 (0.35) | P2RX4MAPK1LMNATSHRSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146230-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-12-21 | — | — | WO | claimed |