Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.65 |
| ▸ | TUBB | P07437 | 4/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PKLR | P30613 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 3/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966640 | 0.90 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1969357 | 0.81 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1968349 | 0.81 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1964838 | 0.79 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25416714 | 0.78 | ADRA1B (0.91) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2995123 | 0.78 | TUBB4A (0.93) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1969449 | 0.78 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1971979 | 0.78 | NR1H4 (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL998603 | 0.77 | ADRA1B (0.73) | PKMADRA1BBACE1BACE2NPC1 | |
| SCHEMBL1972325 | 0.76 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067711-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS FOR MODULATING TRPV1 | AMPHORA DISCOVERY CORPORATION (US) | 2007-06-14 | — | — | WO | claimed |
| WO-2007067711-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS FOR MODULATING TRPV1 | AMPHORA DISCOVERY CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |