SCHEMBL536776

SCHEMBL536776

[CH2]CC(CCC)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.43
LMNA P02545 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
HRH1 P35367 6/20 0.38
HTR2A P28223 5/20 0.38
SIGMAR1 Q99720 1/20 0.37
TAAR1 Q96RJ0 2/20 0.35
RIPK1 Q13546 1/20 0.35
CCR5 P51681 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5259569 0.88 POLB (0.42) AOC3LMNAHRH1HTR2ASIGMAR1
SCHEMBL1263573 0.86 AOC3 (0.48) AOC3LMNAESR1ESR2HRH1
SCHEMBL8824341 0.86 SIGMAR1 (0.42) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL3375650 0.85 AOC3 (0.42) AOC3LMNAESR1ESR2HRH1
SCHEMBL7469930 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL5563476 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL2761416 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL7643903 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL28188782 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL28188186 0.84 NR1I2 (0.44) HTR2ASIGMAR1OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1738829-B New 2',5'-oligoadenylic acid analog SANKYO CO 2012-11-28 CN claimed
CN-108211422-B Device and method for reducing caprolactam in benzene extraction raffinate 阳煤集团太原化工新材料有限公司 2024-04-26 CN disclosed
CN-117916589-A Analytical method for evaluating purity of indigoid 阿奇维生命科学公司 2024-04-19 CN disclosed
CN-113710637-B Preparation method of biaryl phosphine 日本化学工业株式会社 2023-10-24 CN disclosed
CN-111655708-B 2, 3-biphosphinopyrazine derivative, process for producing the same, complex compound, catalyst, and process for producing organoboron compound 日本化学工业株式会社 2023-08-25 CN disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
CN-111465662-B Aqueous dispersion of coloured particles 三菱铅笔株式会社 2023-05-26 CN disclosed
US-20220402875-A1 S1P3 Antagonists TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2022-12-22 US disclosed
CN-111032668-B Optically active 2,3-bisphosphinylpyrazine derivative, process for producing the same, transition metal complex, and process for producing organoboron compound 日本化学工业株式会社 2022-10-14 CN disclosed
CN-86102877-A The method for preparing bicyclic pyrazolidinones 1986-10-29 CN disclosed
CN-86103619-A The preparation method of the bicyclic pyrazolidinones that 7-replaces 1986-10-29 CN disclosed
US-4481276-A ARGON LASER FUJI PHOTO FILM CO., LTD. (JP) 1984-11-06 US disclosed
EP-0109291-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1984-05-23 EP disclosed
US-4399211-A ACRYLIC OLIGOESTER, DIBASIC ACID, POLYOL AND PROMOTER FUJI PHOTO FILM CO., LTD. (JP) 1983-08-16 US disclosed
US-4367280-A AROMATIC CARBONYL COMPOUND AND P-DIALKYLAMINO AROMATIC CARBONYL COMPOUND COMBINATION POLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1983-01-04 US disclosed
US-4290870-A 5-ISOXOLONE, AROMATIC CARBONYL, DIALKYLAMINO AROMATIC CARBONYL OR FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4259432-A HIGH SENSITIVITY TO ULTRAVIOLET RADIATION AND ARGON LASER RAYS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-31 US disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402875-A1 S1P3 Antagonists S1PR3, S1PR5, S1PR1 AOC3 1261/4885LMNA 1938/4885ESR1 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.