SCHEMBL3375650

SCHEMBL3375650

[CH2]CCC(CCC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.42
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
LMNA P02545 1/20 0.39
HRH1 P35367 6/20 0.36
HTR2A P28223 5/20 0.36
SIGMAR1 Q99720 1/20 0.36
TAAR1 Q96RJ0 2/20 0.34
RIPK1 Q13546 1/20 0.34
CCR5 P51681 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
OPRL1 P41146 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4354924 0.89 HRH1 (0.42) LMNAHRH1HTR2ATAAR1
SCHEMBL1263573 0.89 AOC3 (0.48) AOC3ESR1ESR2LMNAHRH1
SCHEMBL6110984 0.88 POLB (0.41) AOC3LMNAHRH1HTR2ASIGMAR1
SCHEMBL3316490 0.88 AOC3 (0.40) AOC3ESR1ESR2LMNAHRH1
SCHEMBL9276354 0.87 AOC3 (0.47) AOC3ESR1ESR2LMNAHRH1
SCHEMBL15563657 0.86 SIGMAR1 (0.41) HTR2ASIGMAR1OPRM1OPRD1OPRK1
SCHEMBL17183765 0.86 SIGMAR1 (0.41) AOC3ESR1ESR2LMNAHRH1
SCHEMBL15061554 0.85 LMNA (0.45) LMNAHRH1HTR2ASIGMAR1TAAR1
SCHEMBL536776 0.85 AOC3 (0.43) AOC3ESR1ESR2LMNAHRH1
SCHEMBL536830 0.85 LMNA (0.45) LMNAHRH1HTR2ASIGMAR1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024108186-A2 PRODUCTION OF HYDROGEN FROM CARBOHYDRATES USING VIOLOGEN CATALYSTS WATT POWER INC. (US) 2024-05-23 WO disclosed
US-20210205199-A1 Dermatological Cosmetic Composition Comprising an SDKP Peptide or an Analog Thereof RPM DERMATOLOGIE (FR) 2021-07-08 US disclosed
WO-2021107870-A1 ANTIMICROBIAL AGENT, COATING FORMULATION, COMPOSITE SURFACE COATING AND METHODS OF PREPARING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2021-06-03 WO disclosed
EP-3239111-B1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM CORP (JP) 2021-02-17 EP disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
US-10035927-B2 Coloring composition for decoration, decorative material, base material having decorative material, transfer material, touch panel, and information display device FUJIFILM CORPORATION (JP) 2018-07-31 US disclosed
US-9988349-B2 Direct stereospecific synthesis of unprotected aziridines from olefins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-06-05 US disclosed
EP-1753708-B1 NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME UNIV BRIGHAM YOUNG (US) 2018-02-21 EP disclosed
EP-3239111-A1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM Corporation (JP) 2017-11-01 EP disclosed
US-9802902-B2 Antifungal compound AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-31 US disclosed
EP-1278716-A1 CYCLOHEXYLAMINE DERIVATIVE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2003-01-29 EP disclosed
US-20030018021-A1 Piperidine derivatives as subtype selective N-methyl-D-aspartate antagonists KORNBERG BRIAN EDWARD (US) 2003-01-23 US disclosed
US-20030004212-A1 Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists DEORAZIO RUSSELL JOSEPH (US) 2003-01-02 US disclosed
EP-1251128-A1 Cyclohexylamine derivatives as subtype selective N-methyl-D-aspartate antagonists WARNER-LAMBERT COMPANY (US) 2002-10-23 EP disclosed
WO-2002050070-A2 PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed
WO-2001094321-A1 BICYCLIC CYCLOHEXYLAMINES AND THEIR USE AS NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-12-13 WO disclosed
WO-2001092239-A1 BICICLIC CYCLOHEXYLAMINES AND THEIR USE AS NMDA RECEPTOR ANTOGONISTS WARNER-LAMBERT COMPANY (US) 2001-12-06 WO disclosed
WO-2001092204-A1 CYCLOHEXYLAMINE DERIVATIVES AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-12-06 WO disclosed
WO-2001081295-A1 CYCLOHEXYLAMINE DERIVATIVE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-11-01 WO disclosed
US-4859759-A Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent KIMBERLY-CLARK CORPORATION (US) 1989-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004212-A1 Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists GLRB, GRIN1, GRIN2B AOC3 4392/4885ESR1 1648/4885ESR2 1139/4885
US-20210205199-A1 Dermatological Cosmetic Composition Comprising an SDKP Peptide or an Analog Thereof CUTA, SDAD1, SDCBP AOC3 3261/4885ESR1 4638/4885ESR2 4312/4885
US-20030018021-A1 Piperidine derivatives as subtype selective N-methyl-D-aspartate antagonists GRIN1, OPRD1, OPRM1 AOC3 4650/4885ESR1 3014/4885ESR2 2383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.