Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359783 | 0.90 | MAPT (0.49) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5368271 | 0.86 | MAPK1 (0.53) | SMN1; SMN2MAPTKMT2AMAPK1LMNA | |
| SCHEMBL5368110 | 0.80 | MAPT (0.57) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5367210 | 0.77 | MAPK1 (0.72) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL21708265 | 0.76 | MAPT (0.62) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5360419 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ATDP1PKM | |
| SCHEMBL5370473 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2MAPTKMT2AMAPK1PKM | |
| SCHEMBL17934215 | 0.74 | MAPT (0.62) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5362108 | 0.74 | KMT2A (0.54) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8752415 | 0.73 | MAPT (0.65) | SMN1; SMN2MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | SI, ATP6AP1, HRH2 | SMN1; SMN2 2675/4885MAPT 4649/4885MEN1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.