SCHEMBL5368446

SCHEMBL5368446

[CH2]C(O)(CCOC(=O)C(=C)C)CCOC(=O)C(=C)C

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4952891 0.86 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10349505 0.85 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3688925 0.83 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL22686158 0.83 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL18051644 0.83 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26002227 0.83 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8965485 0.81 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL438464 0.81 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8966011 0.80 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7625934 0.80 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441803-A1 OPTICAL LAMINATE STRUCTURE, HEAD-UP DISPLAY SYSTEM IN WHICH SAME IS USED, AND OPTICAL REFLECTION FILM Nippon Kayaku Kabushiki Kaisha (JP) 2019-02-13 EP disclosed
US-9605143-B2 Resin composition for formation of optical waveguide, resin film for formation of optical waveguide which comprises the resin composition, and optical waveguide produced using the resin composition or the resin film HITACHI CHEMICALS COMPANY, LTD. (JP) 2017-03-28 US disclosed
US-20130223803-A1 RESIN COMPOSITION FOR FORMATION OF OPTICAL WAVEGUIDE, RESIN FILM FOR FORMATION OF OPTICAL WAVEGUIDE WHICH COMPRISES THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE PRODUCED USING THE RESIN COMPOSITION OR THE RESIN FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-08-29 US disclosed
WO-2007043570-A1 ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION FOR FILM PROTECTION LAYER, FILM USING SAME AND OPTICAL SHEET DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-19 WO disclosed