SCHEMBL5369092

SCHEMBL5369092

Cc1ncc([N+](=O)[O-])n1CC(O)CO

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.77
MAPK1 P28482 2/20 0.74
ATM Q13315 1/20 0.74
ALDH1A1 P00352 2/20 0.64
LMNA P02545 2/20 0.64
THRB P10828 1/20 0.64
TSHR P16473 1/20 0.64
CA1 P00915 4/20 0.51
CA2 P00918 4/20 0.51
CA9 Q16790 4/20 0.51
GAA P10253 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GLA P06280 1/20 0.51
KDM4E B2RXH2 1/20 0.48
CA12 O43570 3/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30174104 0.92 CHRM1 (0.83) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL7713064 0.88 CHRM1 (0.77) CHRM1MAPK1ATMALDH1A1LMNA
Ornidazole SCHEMBL15158379 0.87 CHRM1 (1.00) CHRM1MAPK1ATMALDH1A1LMNA
Ornidazole SCHEMBL43039 0.87 CHRM1 (1.00) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL27714481 0.87 CHRM1 (0.75) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL25121459 0.87 CHRM1 (0.75) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL16367304 0.87 CHRM1 (0.75) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL16367305 0.87 CHRM1 (0.75) CHRM1MAPK1ATMALDH1A1LMNA
Ornidazole SCHEMBL15158378 0.87 CHRM1 (1.00) CHRM1MAPK1ATMALDH1A1LMNA
SCHEMBL25727284 0.87 CHRM1 (0.75) CHRM1MAPK1ATMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN claimed
CN-115561347-A High performance liquid chromatography detection method for related substances of morpholine ornidazole raw material medicine 山东齐都药业有限公司 2023-01-03 CN claimed
CN-112213407-B Detection method of levoornidazole related substances 南京卡文迪许生物工程技术有限公司 2022-08-09 CN claimed
WO-2021058014-A1 ORNIDAZOLE PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND USE THEREOF 扬子江药业集团南京海陵药业有限公司 2021-04-01 WO claimed
CN-112569229-A Preparation containing ornidazole compound and preparation method and application thereof 扬子江药业集团南京海陵药业有限公司 2021-03-30 CN claimed
CN-112569230-A Ornidazole pharmaceutical composition with high safety as well as preparation method and application thereof 扬子江药业集团南京海陵药业有限公司 2021-03-30 CN claimed
CN-112569228-A Pharmaceutical composition containing ornidazole compounds and preparation method and application thereof 扬子江药业集团南京海陵药业有限公司 2021-03-30 CN claimed
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN disclosed
CN-116448935-A High performance liquid chromatography for simultaneously detecting and separating five high concentration ornidazole injection impurities 山东海雅医药科技有限公司 2023-07-18 CN disclosed
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN disclosed
CN-113759002-B Separation and detection method for isomers in levoornidazole or precursor compound thereof 扬子江药业集团南京海陵药业有限公司 2023-03-24 CN disclosed
CN-115561347-A High performance liquid chromatography detection method for related substances of morpholine ornidazole raw material medicine 山东齐都药业有限公司 2023-01-03 CN disclosed
CN-112213407-B Detection method of levoornidazole related substances 南京卡文迪许生物工程技术有限公司 2022-08-09 CN disclosed
CN-110917135-A Solvent system capable of effectively dissolving ornidazole or levoornidazole and injection thereof 西南大学 2020-03-27 CN disclosed
CN-101239951-B 1-(2,3-dihydroxypropyl)-2-methyl-5-nitroimidazole compound and its preparation method and use SICHUAN BAILI PHARMACEUTICAL CO LTD 2011-01-26 CN disclosed
CN-101239951-B 1-(2,3-dihydroxypropyl)-2-methyl-5-nitroimidazole compound and its preparation method and use SICHUAN BAILI PHARMACEUTICAL CO LTD 2011-01-26 CN disclosed
CN-101239951-A 1-(2,3-dihydroxypropyl)-2-methyl-5-nitroimidazole compound and its preparation method and use SICHUAN BAILI PHARMACEUTICAL C (CN) 2008-08-13 CN disclosed
CN-101239951-A 1-(2,3-dihydroxypropyl)-2-methyl-5-nitroimidazole compound and its preparation method and use SICHUAN BAILI PHARMACEUTICAL C (CN) 2008-08-13 CN disclosed
US-7238212-B2 Imidazole compounds and use of these compounds for dyeing keratinous fibers L'OREAL, S.A. (FR) 2007-07-03 US disclosed
US-20050011019-A1 Novel imidazole compounds and use of these compounds for dyeing keratinous fibers L'OREAL, S.A. (FR) 2005-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050011019-A1 Novel imidazole compounds and use of these compounds for dyeing keratinous fibers KRT18, VIM, NDUFS6 CHRM1 2225/4885MAPK1 2658/4885ATM 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.