Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174104 | 0.92 | CHRM1 (0.83) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL16367305 | 0.90 | CHRM1 (0.75) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL16367304 | 0.90 | CHRM1 (0.75) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL5369092 | 0.88 | CHRM1 (0.77) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL25121459 | 0.87 | CHRM1 (0.75) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL16367328 | 0.87 | MAPK1 (0.72) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| Ornidazole SCHEMBL15158378 | 0.87 | CHRM1 (1.00) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| Ornidazole SCHEMBL15158379 | 0.87 | CHRM1 (1.00) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| Ornidazole SCHEMBL43039 | 0.87 | CHRM1 (1.00) | CHRM1MAPK1ATMLMNAALDH1A1 | |
| SCHEMBL27714481 | 0.87 | CHRM1 (0.75) | CHRM1MAPK1ATMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | AUCKLAND UNISERVICES LTD (NL) | 2015-01-08 | — | — | US | disclosed |
| US-6423707-B1 | Nitroimidazole ester analogues and therapeutic applications | CALIFORNIA PACIFIC MEDICAL CENTER | 2002-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | CBR1, CBR3, BLVRB | CHRM1 3336/4885MAPK1 3155/4885ATM 4802/4885 |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | CHRM1 4445/4885MAPK1 4332/4885ATM 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.