Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364125 | 1.00 | SIGMAR1 (0.44) | SIGMAR1HCRTR1HCRTR2GRM2HSP90AA1 | |
| SCHEMBL339247 | 1.00 | SIGMAR1 (0.44) | SIGMAR1HCRTR1HCRTR2GRM2HSP90AA1 | |
| SCHEMBL342217 | 0.86 | HTR2A (0.46) | — | |
| SCHEMBL5369190 | 0.86 | HTR2A (0.46) | — | |
| SCHEMBL5366198 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL341644 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL5379739 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL340561 | 0.85 | SIGMAR1 (0.45) | SIGMAR1HCRTR1HCRTR2GRM2 | |
| SCHEMBL342499 | 0.83 | SIGMAR1 (0.45) | SIGMAR1HCRTR1HCRTR2GRM2HSP90AA1 | |
| SCHEMBL339898 | 0.82 | SIGMAR1 (0.43) | SIGMAR1HCRTR1HCRTR2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217719-B2 | Spiroazacyclic compounds as monoamine receptor modulators | ACADIA PHARMACEUTICALS INC. (US) | 2007-05-15 | — | — | US | claimed |