SCHEMBL5370187

SCHEMBL5370187

O=C(CCc1ccc(O)c(O)c1)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 1/20 0.54
ACE P12821 3/20 0.53
FOLH1 Q04609 2/20 0.51
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
ERCC1 P07992 1/20 0.49
ERCC4 Q92889 1/20 0.49
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
MME P08473 3/20 0.48
YARS1 P54577 1/20 0.48
GRIA1 P42261 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7709347 1.00 NAALAD2 (0.54) NAALAD2ACEFOLH1CA1CA2
SCHEMBL7703636 0.95 MME (0.50) NAALAD2ACEFOLH1CA1CA2
SCHEMBL28794655 0.95 CA1 (0.53) NAALAD2ACEFOLH1CA1CA2
SCHEMBL4147882 0.90 NAALAD2 (0.61) NAALAD2ACEFOLH1CA1CA2
SCHEMBL4147877 0.90 NAALAD2 (0.61) NAALAD2ACEFOLH1CA1CA2
SCHEMBL4147927 0.86 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147924 0.86 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147417 0.86 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147413 0.86 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL5370755 0.85 ERCC1 (0.52) CA1CA2ERCC1ERCC4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223793-B2 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2007-05-29 US disclosed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH NAALAD2 914/4885ACE 1230/4885FOLH1 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.