Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | YARS1 | P54577 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709347 | 0.95 | NAALAD2 (0.54) | MMENAALAD2GRIA1ACEYARS1 | |
| SCHEMBL5370187 | 0.95 | NAALAD2 (0.54) | MMENAALAD2GRIA1ACEYARS1 | |
| SCHEMBL28794655 | 0.90 | CA1 (0.53) | MMENAALAD2GRIA1ACEFOLH1 | |
| SCHEMBL7554886 | 0.88 | GRIA1 (0.55) | GRIA1 | |
| SCHEMBL4147877 | 0.86 | NAALAD2 (0.61) | MMENAALAD2GRIA1ACECPA1 | |
| SCHEMBL4147882 | 0.86 | NAALAD2 (0.61) | MMENAALAD2GRIA1ACECPA1 | |
| SCHEMBL4147417 | 0.82 | ITGB3 (0.62) | MMENAALAD2GRIA1ACEFOLH1 | |
| SCHEMBL4147924 | 0.82 | ITGB3 (0.62) | MMENAALAD2GRIA1ACEFOLH1 | |
| SCHEMBL4147927 | 0.82 | ITGB3 (0.62) | MMENAALAD2GRIA1ACEFOLH1 | |
| SCHEMBL4147413 | 0.82 | ITGB3 (0.62) | MMENAALAD2GRIA1ACEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |