SCHEMBL5370189

SCHEMBL5370189

CC(C)(C)Sc1cccc(C=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
UNG P13051 1/20 0.40
CYP2A6 P11509 2/20 0.38
SRC P12931 1/20 0.36
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
MAOA P21397 3/20 0.35
MAOB P27338 3/20 0.35
BRD4 O60885 1/20 0.35
RAB9A P51151 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 1/20 0.33
AR P10275 1/20 0.33
SLC6A4 P31645 1/20 0.33
TYR P14679 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6779760 0.81 UNG (0.46) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL7317616 0.81 TP53 (0.48) ALDH1A1TDP1TSHRARSLC6A4
SCHEMBL7317610 0.81 AR (0.33) ARSLC6A4KDM4E
SCHEMBL1074727 0.81 ALDH1A1 (0.44) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL30540204 0.81 ALDH1A1 (0.44) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL31351861 0.79 SLC6A4 (0.42) ARSLC6A4KDM4E
SCHEMBL29951214 0.78 ALDH1A1 (0.56) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL711416 0.78 ALDH1A1 (0.56) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL6852138 0.77 ALDH1A1 (0.52) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL5057067 0.75 ALDH1A1 (0.58) ALDH1A1CYP2A6TSHRSLC6A4TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed