SCHEMBL537039

SCHEMBL537039

CCc1ccccc1C(=O)OC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
LMNA P02545 3/20 0.49
TSHR P16473 7/20 0.47
TDP1 Q9NUW8 2/20 0.42
UTS2R Q9UKP6 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 1/20 0.41
HSD17B10 Q99714 3/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
CLCN2 P51788 1/20 0.40
ITGB1 P05556 1/20 0.40
ITGA5 P08648 1/20 0.40
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20482006 0.98 ALDH1A1 (0.47) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL20481943 0.98 ALDH1A1 (0.47) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL20478154 0.98 ALDH1A1 (0.47) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL28551387 0.91 ALDH1A1 (0.45) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL739158 0.90 TSHR (0.52) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL21066726 0.89 TSHR (0.42) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL21066703 0.89 TSHR (0.42) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL28537032 0.89 HSD17B10 (0.56) ALDH1A1LMNATSHRTDP1HTT
SCHEMBL27770565 0.85 TSHR (0.47) ALDH1A1LMNATSHRTDP1UTS2R
SCHEMBL2778 0.83 TSHR (0.52) ALDH1A1LMNATSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4182737-B1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-07-03 EP disclosed
US-20230273456-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed
US-20230273455-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed
EP-4182737-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-05-24 EP disclosed
EP-4182736-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-05-24 EP disclosed
EP-3514822-B1 METHOD FOR MANUFACTURING FIELD EFFECT TRANSISTOR AND METHOD FOR MANUFACTURING WIRELESS COMMUNICATION DEVICE TORAY INDUSTRIES (JP) 2023-04-26 EP disclosed
EP-3868846-B1 DECORATIVE AND PROTECTIVE COATING COMPOSITION FOR METAL, GLASS AND PLASTIC SUBSTRATES EPG F (FR) 2022-11-02 EP disclosed
WO-2022168613-A1 NOVEL ORGANIC TITANIUM COMPOUND AND CURING CATALYST 信越化学工業株式会社 2022-08-11 WO disclosed
US-11407903-B2 Alkali-resistant coating for lightweight metals, in particular aluminum EPG (ENGINEERED NANOPRODUCTS GERMANY) AG (DE) 2022-08-09 US disclosed
CN-109476988-B Composition for organic photoelectric device, and display device 三星SDI株式会社 2022-05-10 CN disclosed
US-5434157-A Active against herpes, hepatitis, papovavirus THE UPJOHN COMPANY (US) 1995-07-18 US disclosed
US-5002951-A 2-amino-5-halo-4-pyrimidinol for bactericides and antiprotozoa agent THE UPJOHN COMPANY (US) 1991-03-26 US disclosed
US-4843080-A VASODILATION; CARDIOVASCULAR ACTIVITY; CHEMICAL INTERMEDIATES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1989-06-27 US disclosed
US-4665077-A IMMUNOREGULATORY AGENTS THE UPJOHN COMPANY (US) 1987-05-12 US disclosed
EP-0202774-A2 1,12b-Disubstituted octahydroindolo [2,3-a]-Quinolizine derivatives RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1986-11-26 EP disclosed
US-4619933-A 6-aryl pyrimidines for treating aplastic anemia THE UPJOHN COMPANY (US) 1986-10-28 US disclosed
US-4543248-A Method for immunoregulation with 6-aryl pyrimidine compounds THE UPJOHN COMPANY (US) 1985-09-24 US disclosed
US-4507302-A Method for treating arthritis with 6-aryl pyrimidine compounds THE UPJOHN COMPANY (US) 1985-03-26 US disclosed
US-4176196-A Hypoglycemic arylcyclohexane acetic acids PFIZER INC. (US) 1979-11-27 US disclosed
US-4152230-A PHOTOOXIDATION PROCESS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230273456-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6D, PDE6A ALDH1A1 277/4885LMNA 1560/4885TSHR 4585/4885
US-20230273455-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6A, PDE6D ALDH1A1 311/4885LMNA 1559/4885TSHR 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.