SCHEMBL5370455

SCHEMBL5370455

C=CCCCc1ccccc1Sc1ccccc1CCCC=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.44
SLC6A2 P23975 6/20 0.38
SLC6A4 P31645 6/20 0.38
SLC6A3 Q01959 4/20 0.38
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 4/20 0.35
IFNAR1 P17181 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 2/20 0.33
MAPK1 P28482 2/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33
APOBEC3G Q9HC16 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5538657 0.78 TLR8 (0.45) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL2475358 0.75 GABRA1 (0.45) SLC6A2SLC6A4SLC6A3ALDH1A1LMNA
SCHEMBL8077547 0.74 TLR8 (0.45) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL8062751 0.74 TAAR1 (0.50) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL5538659 0.74 MPO (0.50) TLR8SLC6A4KDM4E
SCHEMBL8063252 0.74 TSHR (0.50) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL19285031 0.74 TLR8 (0.53) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL8076090 0.74 TAAR1 (0.50) TLR8SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL8073132 0.74 TAAR1 (0.50) TLR8ALDH1A1HPGDUSP2TDP1
SCHEMBL8063273 0.74 TAAR1 (0.52) TLR8SLC6A4ALDH1A1HPGDUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed
US-7053159-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2006-05-30 US disclosed
US-20060063898-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby INOUE YOSHIHISA 2006-03-23 US disclosed
US-20020099155-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2002-07-25 US disclosed
EP-1170308-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2002-01-09 EP disclosed