SCHEMBL5370465

SCHEMBL5370465

C=CCCCc1ccccc1S

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.49
ALDH1A1 P00352 2/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC1 Q13547 2/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
HDAC4 P56524 1/20 0.33
LMNA P02545 1/20 0.31
EP300 Q09472 1/20 0.31
KAT2B Q92831 1/20 0.31
KAT5 Q92993 1/20 0.31
KAT8 Q9H7Z6 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552014 0.88 TLR8 (0.37) TLR8ALDH1A1USP2HPGDTDP1
SCHEMBL27952236 0.80 LIPG (0.34)
SCHEMBL6028071 0.77 TLR8 (0.50) TLR8TDP1
SCHEMBL5538657 0.76 TLR8 (0.45) TLR8ALDH1A1USP2HPGDTDP1
SCHEMBL8077547 0.76 TLR8 (0.45) TLR8ALDH1A1USP2HPGDTDP1
SCHEMBL19285031 0.76 TLR8 (0.53) TLR8ALDH1A1USP2HPGDTDP1
SCHEMBL8076090 0.76 TAAR1 (0.50) TLR8ALDH1A1
SCHEMBL8063273 0.76 TAAR1 (0.52) TLR8ALDH1A1USP2HPGDTDP1
SCHEMBL5538659 0.76 MPO (0.50) TLR8EP300KAT2BKAT5KAT8
SCHEMBL8073132 0.76 TAAR1 (0.50) TLR8ALDH1A1USP2HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed
US-7053159-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2006-05-30 US disclosed
US-20060063898-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby INOUE YOSHIHISA 2006-03-23 US disclosed
US-20020099155-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2002-07-25 US disclosed
EP-1170308-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2002-01-09 EP disclosed