Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373846 | 0.93 | KDM4E (0.53) | F10KDM4EALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL5372356 | 0.91 | F10 (0.60) | F10PRSS1TSHRF2TP53 | |
| SCHEMBL5375602 | 0.87 | CYP2C19 (0.55) | F10PRSS1KDM4EALDH1A1TP53 | |
| SCHEMBL5371300 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2TACR2HTT | |
| SCHEMBL5372968 | 0.83 | TP53 (0.53) | F10PRSS1TSHRTP53 | |
| SCHEMBL5372728 | 0.82 | KDM4E (0.51) | F10PRSS1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5163340 | 0.81 | F10 (0.58) | F10PRSS1ALDH1A1TSHRF2 | |
| SCHEMBL5366864 | 0.81 | F10 (0.63) | F10PRSS1F2 | |
| SCHEMBL5168020 | 0.79 | F10 (0.57) | F10PRSS1F2NPC1 | |
| SCHEMBL5165461 | 0.79 | F10 (0.77) | F10PRSS1ALDH1A1SMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
| US-7273867-B2 | Phenyl derivatives | MERCK PATENT GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | F10 6/4885PRSS1 88/4885KDM4E 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.