Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 6/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294128 | 1.00 | S1PR1 (0.39) | S1PR1NPSR1ALDH1A1MAPTRXFP1 | |
| SCHEMBL4613924 | 0.89 | S1PR1 (0.44) | S1PR1NPSR1ALDH1A1MAPTRXFP1 | |
| SCHEMBL4613923 | 0.89 | S1PR1 (0.44) | S1PR1NPSR1ALDH1A1MAPTRXFP1 | |
| SCHEMBL11316119 | 0.88 | S1PR1 (0.43) | S1PR1NPSR1ALDH1A1MAPTRXFP1 | |
| SCHEMBL5277645 | 0.86 | ALDH1A1 (0.45) | NPSR1ALDH1A1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL11320819 | 0.81 | S1PR1 (0.43) | S1PR1ALDH1A1MAPTPLA2G2ASMN1; SMN2 | |
| SCHEMBL11316106 | 0.81 | CNR2 (0.50) | S1PR1SMN1; SMN2HPGDCNR2CNR1 | |
| SCHEMBL4621389 | 0.74 | ALDH1A1 (0.46) | NPSR1ALDH1A1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL5278253 | 0.72 | CNR1 (0.55) | NPSR1ALDH1A1MAPTSMN1; SMN2CNR2 | |
| SCHEMBL4796779 | 0.70 | LMNA (0.42) | S1PR1NPSR1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294151-B2 | Means and method for dyeing keratin fibres | WELLA AG (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KOYO SEIKO CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KRT18, KLK5, KIT | S1PR1 3958/4885NPSR1 2071/4885ALDH1A1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.