Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28242218 | 1.00 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL11409348 | 1.00 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL497410 | 0.96 | — | — | |
| Sulfuric Acid SCHEMBL28123593 | 0.96 | CA5A (0.55) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL8579392 | 0.96 | CA5A (0.55) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL9316832 | 0.96 | CA5A (0.55) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL27858775 | 0.92 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL27982895 | 0.92 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL22776129 | 0.92 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 | |
| Sulfuric Acid SCHEMBL27939839 | 0.92 | CA5A (0.50) | CA5ACA5BTP53CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971569-B1 | PROCESS FOR ISOLATION OF AN ORGANIC AMINE | DSM IP ASSETS BV (NL) | 2012-02-08 | — | — | EP | disclosed |
| US-7977514-B2 | Process for isolation of an organic amine | DSM IP ASSETS B.V. (NL) | 2011-07-12 | — | — | US | disclosed |
| US-20100274057-A1 | PROCESS FOR ISOLATION OF AN ORGANIC AMINE | ENVALIOR B.V. (NL) | 2010-10-28 | — | — | US | disclosed |
| EP-1971569-A1 | PROCESS FOR ISOLATION OF AN ORGANIC AMINE | DSMIP Assets B.V. (NL) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007079944-A1 | PROCESS FOR ISOLATION OF AN ORGANIC AMINE | DSM IP ASSETS B.V. (NL) | 2007-07-19 | — | — | WO | disclosed |