SCHEMBL5371218

SCHEMBL5371218

C=CCC(C(=O)C(CC=C)c1ccccc1)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.79
SMN1; SMN2 Q16637 3/20 0.43
EPHX1 P07099 1/20 0.43
POLB P06746 1/20 0.42
LMNA P02545 4/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4A O75164 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2D6 P10635 1/20 0.40
SRC P12931 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666893 0.88 CYP2C19 (1.00) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL1458057 0.88 CYP2C19 (1.00) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL1458050 0.88 CYP2C19 (1.00) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL6967261 0.86 CYP2C19 (0.76) CYP2C19SMN1; SMN2EPHX1LMNAHSD17B10
SCHEMBL10959538 0.86 CYP2C19 (0.96) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL1458161 0.86 CYP2C19 (0.96) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL1457969 0.86 CYP2C19 (0.96) CYP2C19SMN1; SMN2EPHX1POLBLMNA
SCHEMBL6423644 0.85 CYP2C19 (0.73) CYP2C19SMN1; SMN2EPHX1LMNAHSD17B10
SCHEMBL9577255 0.85 CYP2C19 (0.73) CYP2C19SMN1; SMN2EPHX1LMNAHSD17B10
SCHEMBL6631805 0.85 CYP2C19 (0.73) CYP2C19SMN1; SMN2EPHX1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed
US-7053159-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2006-05-30 US disclosed
US-20060063898-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby INOUE YOSHIHISA 2006-03-23 US disclosed
US-6992035-B2 Metallocenes, polymerization catalyst systems, their preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2006-01-31 US disclosed
US-20030092925-A1 Metallocenes, polymerization catalyst systems, their preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2003-05-15 US disclosed
US-20020099155-A1 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2002-07-25 US disclosed
EP-1170308-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2002-01-09 EP disclosed
US-6187880-B1 USING SOLID CATALYST SYSTEM PREPARED BY COMBINING A METALLOCENE WITH A SOLUTION OF AN ORGANOALUMINOXANE COCATALYST AND CONDUCTING PREPOLYMERIZATION TO PRODUCE A PREPOLYMERIZED SOLID PHILLIPS PETROLEUM COMPANY 2001-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092925-A1 Metallocenes, polymerization catalyst systems, their preparation, and use WASF2, WEE2, NOTUM CYP2C19 675/4885SMN1; SMN2 3001/4885EPHX1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.