SCHEMBL5371272

SCHEMBL5371272

CCCCC(CCCCCC(C)C)OC(=O)C1(C(=O)O)CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.33
ACE2 Q9BYF1 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR84 Q9NQS5 3/20 0.31
FFAR1 O14842 1/20 0.31
CTSK P43235 3/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
MAPT P10636 1/20 0.30
LCK P06239 1/20 0.30
PPARD Q03181 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5369074 1.00 FAAH (0.33) FAAHACE2MEN1KMT2AGPR84
SCHEMBL25245958 0.97 FAAH (0.35) FAAHACE2GPR84FFAR1MAPT
SCHEMBL17982638 0.95 CETP (0.32)
SCHEMBL5370063 0.93 GPR84 (0.37) FAAHACE2MEN1KMT2AGPR84
SCHEMBL5368458 0.92 GPR84 (0.38) FAAHACE2GPR84FFAR1MAPT
SCHEMBL28334565 0.92 GPR84 (0.38) FAAHACE2GPR84FFAR1MAPT
SCHEMBL5379168 0.89 GPR84 (0.36) FAAHACE2MEN1KMT2AGPR84
SCHEMBL5374405 0.89 GPR84 (0.36) FAAHACE2MEN1KMT2AGPR84
SCHEMBL5370779 0.89 GPR84 (0.36) FAAHACE2MEN1KMT2AGPR84
SCHEMBL2917640 0.86 GPR84 (0.36) FAAHACE2MEN1KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
CN-1356973-A Selected cyclohexane-1, 3-and-1, 4-dicarboxylic acid esters BASF AG (DE) 2002-07-03 CN claimed
CN-100465153-C Selected cyclohexane-1, 3-and-1, 4-dicarboxylic acid esters BASF AG (DE) 2009-03-04 CN disclosed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed
CN-1356973-A Selected cyclohexane-1, 3-and-1, 4-dicarboxylic acid esters BASF AG (DE) 2002-07-03 CN disclosed