SCHEMBL5371340

SCHEMBL5371340

CCCCC(CCCCCCCCCCC(C)C)OC(=O)c1ccc(C(=O)OC(CCCC)CCCCCCCCCCC(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
PRKCA P17252 2/20 0.50
PRKCD Q05655 2/20 0.50
PNLIP P16233 3/20 0.48
ALDH1A1 P00352 3/20 0.43
RARB P10826 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 3/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5371350 0.94 RARB (0.50) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL18485496 0.94 RARB (0.50) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL7859268 0.93 RARB (0.51) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL6901535 0.92 PNLIP (0.50) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL6670608 0.92 PRKCA (0.51) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL16227358 0.92 PNLIP (0.54) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL5373199 0.92 PNLIP (0.54) TSHRPRKCAPRKCDPNLIPALDH1A1
SCHEMBL6672236 0.91 RARB (0.50) TSHRPNLIPALDH1A1RARBMAPT
SCHEMBL6671767 0.91 RARB (0.50) TSHRPNLIPALDH1A1RARBMAPT
SCHEMBL6670588 0.91 RARB (0.50) TSHRPNLIPALDH1A1RARBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
CN-100465153-C Selected cyclohexane-1, 3-and-1, 4-dicarboxylic acid esters BASF AG (DE) 2009-03-04 CN disclosed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed
CN-1356973-A Selected cyclohexane-1, 3-and-1, 4-dicarboxylic acid esters BASF AG (DE) 2002-07-03 CN disclosed