Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625979 | 0.97 | ACE2 (0.36) | EPHX2CTSKCNR1DAGLAACE2 | |
| SCHEMBL27626107 | 0.93 | EPHX2 (0.39) | EPHX2CTSKCNR1DAGLAS1PR5 | |
| SCHEMBL5364963 | 0.93 | EPHX2 (0.39) | EPHX2CTSKCNR1DAGLAS1PR5 | |
| SCHEMBL27646713 | 0.89 | EPHX2 (0.38) | EPHX2S1PR5 | |
| SCHEMBL9876145 | 0.88 | CTSK (0.40) | EPHX2CTSKS1PR5TP53 | |
| SCHEMBL5375229 | 0.87 | EPHX2 (0.46) | EPHX2CTSKCNR1DAGLAACE2 | |
| SCHEMBL9107859 | 0.85 | EPHX2 (0.47) | EPHX2CTSKCNR1DAGLAS1PR5 | |
| SCHEMBL27646678 | 0.84 | EPHX2 (0.43) | EPHX2CTSKCNR1DAGLAACE2 | |
| SCHEMBL27646381 | 0.82 | TSHR (0.35) | ACE2S1PR5TP53GPR84FFAR1 | |
| SCHEMBL27646420 | 0.82 | TSHR (0.35) | ACE2S1PR5TP53GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | claimed |