SCHEMBL5371901

SCHEMBL5371901

O=C[C@H](OC(=O)c1ccc(O)cc1)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA14 Q9ULX7 3/20 0.45
ESR1 P03372 4/20 0.41
ESR2 Q92731 3/20 0.41
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.36
CHRM1 P11229 1/20 0.36
SLC6A2 P23975 1/20 0.36
KDR P35968 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ADRB2 P07550 2/20 0.36
ADRB1 P08588 2/20 0.36
ADRB3 P13945 2/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19150118 0.89 LMNA (0.41) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL16271188 0.87 TSHR (0.47) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL2355030 0.87 TSHR (0.47) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL21798546 0.87 TSHR (0.47) ESR1ESR2ALDH1A1MEN1KMT2A
Bromide SCHEMBL8072032 0.86 TSHR (0.46) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL30426029 0.83 ALOX15 (0.39) ALDH1A1TSHRSMN1; SMN2RAB9APRKCA
SCHEMBL30295382 0.83 TDP1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7149086 0.83 TDP1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7149024 0.82 TSHR (0.49) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL27671082 0.82 TSHR (0.49) ESR1ESR2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005038004-A2 METHOD TO PRODUCT PARA-HYDROXYBENZOIC ACID IN THE STEM TISSUE OF GREEN PLANTS BY USING A TISSUE-SPECIFIC PROMTER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-28 WO claimed
US-20050086712-A1 Method to produce para-hydroxybenzoic acid in the stem tissue of green plants by using a tissue-specific promoter UNIVERSITY OF NORTH TEXAS 2005-04-21 US claimed
US-12247209-B2 Transferase enzymes PLANT BIOSCIENCE LIMITED (GB) 2025-03-11 US disclosed
CN-113278648-B Method for cultivating blue chrysanthemum through cotransporter delphinidin glycoside synthesis related genes 南京农业大学 2023-06-16 CN disclosed
US-20230106588-A1 TRANSFERASE ENZYMES PLANT BIOSCIENCE LIMITED (GB) 2023-04-06 US disclosed
CN-114641573-A Transferases 植物生物科学有限公司 2022-06-17 CN disclosed
EP-3990643-A1 TRANSFERASE ENZYMES Plant Bioscience Limited (GB) 2022-05-04 EP disclosed
US-11085048-B2 Lignification reduction in plants THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-10 US disclosed
WO-2020260475-A1 TRANSFERASE ENZYMES PLANT BIOSCIENCE LIMITED (GB) 2020-12-30 WO disclosed
US-20190300895-A1 LIGNIFICATION REDUCTION IN PLANTS UNITED STATES DEPARTMENT OF ENERGY 2019-10-03 US disclosed
US-20150013033-A1 LIGNIFICATION REDUCTION IN PLANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-01-08 US disclosed
WO-2013010124-A1 LIGNIFICATION REDUCTION IN PLANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-17 WO disclosed
US-7238512-B2 Method to produce para-hydroxybenzoic acid in the stem tissue of green plants by using a tissue-specific promoter E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-03 US disclosed
WO-2005038004-A2 METHOD TO PRODUCT PARA-HYDROXYBENZOIC ACID IN THE STEM TISSUE OF GREEN PLANTS BY USING A TISSUE-SPECIFIC PROMTER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-28 WO disclosed
US-20050086712-A1 Method to produce para-hydroxybenzoic acid in the stem tissue of green plants by using a tissue-specific promoter UNIVERSITY OF NORTH TEXAS 2005-04-21 US disclosed