SCHEMBL5372826

SCHEMBL5372826

N=[C]C1C2C=CC(C2)C1[C]=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5349953 0.69
SCHEMBL5080176 0.69 ALDH1A1 (0.32)
SCHEMBL13409249 0.69
SCHEMBL13409251 0.69
Hydrochloric Acid SCHEMBL8200848 0.60 ALDH1A1 (0.33)
SCHEMBL2250610 0.60
SCHEMBL7902771 0.60
SCHEMBL5353877 0.60
SCHEMBL24451701 0.56
SCHEMBL6724992 0.56 ALDH1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586375-A Method for preparing semaglutin 苏州金顶生物有限公司 2024-02-23 CN claimed
CN-115197312-A Preparation method and intermediate of Somalutide 奥锐特药业(天津)有限公司 2022-10-18 CN claimed
US-10829512-B2 Selective disulfidation reagent using nitrogen-containing compound and method for producing disulfide-containing compound TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2020-11-10 US claimed
EP-0830353-B1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND ABBOTT LAB (US) 2002-04-24 EP claimed
EP-0830353-A1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND Abbott Laboratories (US) 1998-03-25 EP claimed
WO-1996039398-A1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND ABBOTT LABORATORIES (US) 1996-12-12 WO claimed
US-5567823-A Process for the preparation of an HIV protease inhibiting compound ABBOTT LABORATORIES (US) 1996-10-22 US claimed
CN-117586375-A Method for preparing semaglutin 苏州金顶生物有限公司 2024-02-23 CN disclosed
CN-115197312-A Preparation method and intermediate of Somalutide 奥锐特药业(天津)有限公司 2022-10-18 CN disclosed
US-10829512-B2 Selective disulfidation reagent using nitrogen-containing compound and method for producing disulfide-containing compound TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2020-11-10 US disclosed
US-20190169228-A1 SELECTIVE DISULFIDATION REAGENT USING NITROGEN-CONTAINING COMPOUND AND METHOD FOR PRODUCING DISULFIDE-CONTAINING COMPOUND TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2019-06-06 US disclosed
US-7223518-B2 Compositions and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2007-05-29 US disclosed
WO-2004108769-A2 COMPOSITION AND METHOD OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2004-12-16 WO disclosed
US-20040248034-A1 Compositions and methods of use thereof HENDERSON CLIFFORD L (US) 2004-12-09 US disclosed
EP-0830353-B1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND ABBOTT LAB (US) 2002-04-24 EP disclosed
EP-0830353-A1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND Abbott Laboratories (US) 1998-03-25 EP disclosed
WO-1996039398-A1 PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND ABBOTT LABORATORIES (US) 1996-12-12 WO disclosed
US-5567823-A Process for the preparation of an HIV protease inhibiting compound ABBOTT LABORATORIES (US) 1996-10-22 US disclosed
EP-0038117-A1 Methods for preparing anti-hypertensive agents UNIVERSITY OF MIAMI (US) 1981-10-21 EP disclosed