SCHEMBL6724992

SCHEMBL6724992

C1=CC2CC1C1CCC3C4C=CC(C4)C3CCC21

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
HSD11B1 P28845 1/20 0.37
TDP1 Q9NUW8 2/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19689443 1.00 ALDH1A1 (0.46) ALDH1A1HSD11B1TDP1POLBAPEX1
SCHEMBL5491384 1.00
SCHEMBL200160 0.86 HSD11B1 (0.43) ALDH1A1HSD11B1
SCHEMBL199996 0.86 ALDH1A1 (0.42) ALDH1A1HSD11B1
SCHEMBL3986309 0.86 ALDH1A1 (0.42) ALDH1A1HSD11B1
SCHEMBL200957 0.83 HSD11B1 (0.47) ALDH1A1HSD11B1
SCHEMBL19947463 0.83 HSD11B1 (0.47) ALDH1A1HSD11B1
SCHEMBL2385638 0.81 ALDH1A1 (0.44) ALDH1A1HSD11B1
SCHEMBL2385641 0.81 ALDH1A1 (0.44) ALDH1A1HSD11B1
SCHEMBL9805146 0.81 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744462-A1 COMPOSITION Merck Patent GmbH (DE) 2026-05-20 EP disclosed
EP-4605438-A1 COMPOSITION Merck Patent GmbH (DE) 2025-08-27 EP disclosed
WO-2025012183-A1 COMPOSITION MERCK PATENT GMBH (DE) 2025-01-16 WO disclosed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
WO-2023097092-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 WO disclosed
WO-2022157591-A1 ARTICLE AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-07-28 WO disclosed
WO-2022101746-A1 CURABLE COMPOSITION AND ABRASIVE ARTICLES MADE USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-05-19 WO disclosed
US-20220010157-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2022-01-13 US disclosed
US-10712661-B2 Negative tone photosensitive compositions PROMERUS, LLC (US) 2020-07-14 US disclosed
US-20170357156-A1 NEGATIVE TONE PHOTOSENSITIVE COMPOSITIONS PROMERUS, LLC (US) 2017-12-14 US disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
US-6677175-B2 CURING A CLADDING LAYER TO FORM A CORE/CLADDING COMBINATION AND REMOVING THE CORE/CLADDING TO EXPOSE A PORTION OF THE CORE THAT HAS REFRACTIVE INDEX .05% HIGHER THAN THE CURED CLADDING COMPOSITION PROMERUS, LLC 2004-01-13 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
US-5068296-A Crosslinked copolymers for molding materials HERCULES INCORPORATED (US) 1991-11-26 US disclosed
US-5006616-A Metathesis polymerized copolymer HERCULES INCORPORATED (US) 1991-04-09 US disclosed
EP-0287762-A2 Methathesis polymerized copolymer HERCULES INCORPORATED (US) 1988-10-26 EP disclosed