Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468031 | 1.00 | CYP2A6 (0.62) | CYP2A6PDCD1CD274HSD11B1ALDH1A1 | |
| O-Xylene SCHEMBL28322428 | 0.94 | CYP2A6 (0.56) | CYP2A6PDCD1CD274HSD11B1ALDH1A1 | |
| SCHEMBL28322430 | 0.84 | CYP2A6 (0.54) | CYP2A6PDCD1CD274HSD11B1ALDH1A1 | |
| SCHEMBL10961604 | 0.83 | ALDH1A1 (0.52) | CYP2A6HSD11B1ALDH1A1IDO1PTGS2 | |
| SCHEMBL25785668 | 0.83 | PDCD1 (0.64) | CYP2A6PDCD1CD274ALDH1A1PTGS2 | |
| SCHEMBL11057698 | 0.82 | CYP2A6 (0.50) | CYP2A6PDCD1CD274HSD11B1ALDH1A1 | |
| SCHEMBL28400046 | 0.81 | TP53 (0.46) | CYP2A6HSD11B1ALDH1A1IDO1PTGS2 | |
| Ammonia Solution, Strong SCHEMBL27977448 | 0.80 | CYP2A6 (0.48) | CYP2A6PDCD1CD274HSD11B1ALDH1A1 | |
| SCHEMBL31156157 | 0.79 | SRD5A2 (0.47) | ALDH1A1PTGS2HPGDLMNAMEN1 | |
| SCHEMBL23628571 | 0.78 | CYP2A6 (1.00) | CYP2A6HSD11B1ALDH1A1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606191-A | Preparation method of 3-chloro-2-methyl biphenyl | 辽宁氟托新能源材料有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-111187144-A | Synthetic method of 3-chloro-2-methyl biphenyl and derivatives thereof | 江苏优嘉植物保护有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-110204415-A | A kind of synthetic method of 3- chloro-2-methyl biphenyl | 王海峻 | 2019-09-06 | — | — | CN | claimed |
| CN-106833260-A | A kind of insulated metal product surface processing method | 安徽宝恒新材料科技有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-103626629-B | Rectification method of 3-chlorine-2-methyl diphenyl | YANCHENG CONFIDENT BIOCHEMICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-102964217-B | Method for preparing 2-methyl-3-biphenylmethyanol through continuous Grignard and hydroxylation reactions | JIANGSU YOUJIA CHEMISTRY CO., LTD. (CN) | 2014-10-01 | — | — | CN | claimed |
| CN-103626629-A | Rectification method of 3-chlorine-2-methyl diphenyl | YANCHENG CONFIDENT BIOCHEMICAL TECHNOLOGY CO LTD | 2014-03-12 | — | — | CN | claimed |
| CN-101704723-B | Preparation method of hydroxymethyl substitutent o-alkyl biphenyl and intermediate thereof | SHANGHAI WANSU CHEMICAL CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-102964217-A | Method for preparing 2-methyl-3-biphenylmethyanol through continuous Grignard and hydroxylation reactions | JIANGSU YANGNONG CHEMICAL CO | 2013-03-13 | — | — | CN | claimed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| EP-0152450-B1 | CATALYZED GRIGNARD COUPLING PROCESS | FMC Corporation (US) | 1989-05-03 | — | — | EP | claimed |
| EP-0152450-A4 | CATALYZED GRIGNARD COUPLING PROCESS. | FMC CORP (US) | 1985-12-05 | — | — | EP | claimed |
| EP-0152450-A1 | CATALYZED GRIGNARD COUPLING PROCESS. | FMC CORP (US) | 1985-08-28 | — | — | EP | claimed |
| US-4507513-A | NICKEL ACETYLACETONE AS CATALYST | FMC CORPORATION (US) | 1985-03-26 | — | — | US | claimed |
| WO-1985001045-A1 | CATALYZED GRIGNARD COUPLING PROCESS | FMC CORPORATION (US) | 1985-03-14 | — | — | WO | claimed |
| US-4465879-A | 3-HALO-2-METHYL(1,1*-BIPHENYL) FROM HALOBENZENE WITH 3-HALO-2-METHYLPHENYLMAGNESIUM HALIDE AND PALLADIUM CATALYST | FMC CORPORATION (US) | 1984-08-14 | — | — | US | claimed |
| CN-113429256-B | Preparation method of bifenthrin insecticide intermediate | 湖南华腾制药有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-0021228-A1 | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | CYP2A6 614/4885PDCD1 4374/4885CD274 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.