SCHEMBL10961604

SCHEMBL10961604

Cc1c(Cl)cccc1-c1ccccc1-c1cccc(Cl)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
IDO1 P14902 1/20 0.50
LMNA P02545 4/20 0.45
TSHR P16473 1/20 0.45
HSD11B1 P28845 2/20 0.45
CYP2A6 P11509 3/20 0.44
BRD4 O60885 1/20 0.41
CREBBP Q92793 1/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
PLA2G7 Q13093 1/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 3/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
MT-CO2 P00403 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13378358 0.88 ALDH1A1 (0.46) ALDH1A1IDO1LMNATSHRHSD11B1
SCHEMBL7394559 0.84 KCNN4 (0.44) ALDH1A1IDO1HSD11B1BRD4CREBBP
SCHEMBL29468031 0.83 CYP2A6 (0.62) ALDH1A1IDO1LMNATSHRHSD11B1
SCHEMBL5373779 0.83 CYP2A6 (0.62) ALDH1A1IDO1LMNATSHRHSD11B1
SCHEMBL112040 0.80
SCHEMBL2478161 0.80 ALDH1A1 (0.45) ALDH1A1IDO1LMNATSHRHSD11B1
SCHEMBL23198751 0.78 PLA2G7 (0.50) ALDH1A1IDO1LMNATSHRHSD11B1
O-Xylene SCHEMBL28322428 0.78 CYP2A6 (0.56) ALDH1A1IDO1TSHRHSD11B1CYP2A6
Fluoride SCHEMBL28877073 0.77 ALDH1A1 (0.62) ALDH1A1IDO1LMNATSHRCYP2A6
Hydrochloric Acid SCHEMBL10426264 0.77 ALDH1A1 (0.62) ALDH1A1IDO1LMNATSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4507513-A NICKEL ACETYLACETONE AS CATALYST FMC CORPORATION (US) 1985-03-26 US disclosed